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Many nutrients face challenges in crossing the intestinal barrier and reaching their intended target sites within the body. Factors such as poor solubility, large molecular size, and enzymatic degradation can impede their absorption, leading to suboptimal nutrient uptake and potential nutrient deficiencies.
At the center of this study is one molecule: nicotinamide adenine dinucleotide (NAD+), a coenzyme critical for human cellular function and health. In this comprehensive look, we will discover what NAD+ is, explore the key importance sirtuins and PARPs play, discuss ways through which we can keep naturally high NAD+ levels, and look at how NAD3®...
The journey of collagen genesis begins with the transcriptional activation of key genes encoding collagen precursors. Here, NAD+ takes centre stage, fuelling the activity of sirtuins, a family of longevity-associated proteins known for their role in gene regulation and DNA repair.